The study result also showed that PTEN was upregulated in serum of PCOS-nonobese patients relative to healthy-nonobese participants; PTEN was upregulated in serum of PCOS-obese patients relative to healthy-obese participants; PTEN expression in serum of PCOS-obese patients was higher than that of PCOS-nonobese patients. Here, PTEN is linked to polycystic ovary syndrome.