In addition, there are several studies investigated the association of EIF4E and human tumors such as lung cancer (Seki et al., 2010), colorectal cancer (Niu et al., 2014; Diab-Assaf et al., 2015; Slattery et al., 2017), breast cancer (Heikkinen et al., 2013; Hu et al., 2014), and head and neck carcinoma (Nathan et al., 1997; Culjkovic and Borden, 2009). The gene discussed is EIF4E; the disease is head and neck carcinoma.