The 247 kb microduplication at 22q11.22 in the patient CG0903 interrupted the TOP3B, whose mutations were associated with several neurodevelopmental disorders including schizophrenia, autism, and epilepsy (Stoll et al., 2013; Ahmad et al., 2017; Daghsni et al., 2018). Here, TOP3B is linked to schizophrenia.