Similarly scRNAseq of ZnT8 reactive cells from the peripheral blood of people with T1D showed similar GEX profiles to healthy controls, indicating that these peripheral T cells may not be playing a driving role in T1D, although T1D patients had higher expression of aryl hydrocarbon receptor (AHR) and aurora kinase A (AURKA) and lower expression of RORA (26). Here, RORA is linked to type 1 diabetes mellitus.