IL22 and infection: The role of ILC3s in the defence against C. difficile was studied in the murine model and although upregulation of the expression of ILC1- or ILC3-associated proteins in the large intestine was detected following C. difficile infection; selective loss of ILC3s (Rorc−/− mice) or ILC3 effector molecules (Il-22−/− and Il-17−/− mice) did not affect the survival or the severity of the infection.