CASP8 and neoplasm: The expression analysis results showed that compared with the control group, the expression of CASP3, CASP6, CASP8, GSDMD, IL18, NOD2, and PYCARD was significantly higher in the tumor group, whereas that of CASP1, CASP4, ELANE, GPX4, GSDMB, GSDMC, GSEMD, IL1B, IL6, NLRP1, NLRP3, NOD1, PJVK, and SCAF11 was significantly lower (Figure 2B).