Differences in the immunological parameters among COVID-19 and non-COVID-19 cases were explored by a univariate linear-log regression model and a multivariate model adjusted by age (Supplementary Table S1): the two groups differed in their percentages of both T (CD4 and CD8) and B-activated cells and Tregs and Bregs (Supplementary Table S1). The gene discussed is CD8A; the disease is COVID-19.