The soluble L-selectin levels detected in circulation were found to be higher in infected than healthy individuals (Kourtis et al., 2000, 2003; Meddows-Taylor et al., 2001; Schramm et al., 2007; Yang et al., 2014), reminisce to elevated soluble selectin found in autoimmune diseases, including rheumatoid arthritis, systemic sclerosis, and systemic lupus erythematosus (Sfikakis et al., 1999; Shimada et al., 2001; Ates et al., 2004). Here, SELL is linked to systemic lupus erythematosus.