Univariate logistic regression showed that the suprasellar volume, total tumor volume, supra-intrasellar ratio, Knosp grade, maximum tumor diameter, tumor-ICA ratio, and V-D value had a significant correlation with the recurrence of NFPAs, while the levels of Ki-67 and other hormones had no statistical correlation with recurrence (Table 3). This evidence concerns the gene MKI67 and neoplasm.