NDUFB6 and Insulin resistance: Palmitate-induced reduction in pAkt-Ser473 was decreased by 35% in Ndufb6 siRNA when compared to control siRNA conditions after EPS exposure (0.64 ± 0.02 vs. 1.10 ± 0.05 AU; p<0.01), indicating that contractions were not able to protect against palmitate-induced insulin resistance after Ndufb6 silencing (Figures 3G, H).