In MRC-5 stimulated with TGF-β - ↓ markers of myofibroblast differentiation (vimentin, α SMA, fibronectin) - ↓oxidative stress (ROS and MDA) In rat exposed to BLM - ↓ markers of myofibroblast differentiation (α SMA) - Improved the induced pulmonary fibrosis. The gene discussed is VIM; the disease is pulmonary fibrosis.