Compared with the control rats, the levels of CD31 and VE-cadherin were significantly decreased, the expressions of α-SMA and vimentin were increased in DCM rats, while CD31 and VE-cadherin were significantly promoted by silencing miR-195-5p, and α-SMA and vimentin were inhibited (all p<0.05; Figure 3A). This evidence concerns the gene VIM and familial dilated cardiomyopathy.