AKT1 and medical procedure: PI3K (F = 113.9, p < 0.001), Akt (F = 13.9, p < 0.001) phosphorylation, and nuclear NF-κB (F = 119.1, p < 0.001) were significantly increased and cytosolic IκB-α (F = 36.1, p < 0.001) was significantly decreased after lung IR injury, and SCH530348 treatment significantly attenuated these effects (Figure 8).