This controversy could in part be due to the phase of epilepsy being investigated, as the negative relationship between mTOR inhibition and Glt1 expression was evident in a subacute phase of epilepsy (Jeong et al., 2021), while the positive relationship between mTOR inhibition and Glt1 stability was reported in a chronic phase of epilepsy (Wang et al., 2017). The gene discussed is MTOR; the disease is epilepsy.