Kir4.1 expression is markedly decreased in several neurological disorders (cf. Scholl et al., 2009; Inyushin et al., 2010; Gilliam et al., 2014), including in striatal cells of Huntington’s disease mice (Tong et al., 2014; Dvorzhak et al., 2016). This evidence concerns the gene KCNJ10 and nervous system disorder.