NRP‐1 is expressed in T cells and dendritic cells (DCs) and is related to their interaction.[68, 69, 70] However, NRP‐1 also maintains Treg survival and inhibits CD8+ T cells during tumorigenesis, which eventually hinders tumor clearance mediated by effector T cells.[68, 69, 70] Its role in tumorigenesis and its potential as a drug target have been confirmed.[71, 72, 73] However, the specific mechanism by which NRP‐1 affect tumorigenesis remains unknown. Here, NRP1 is linked to neoplasm.