Jesus et al. reported a Moroccan girl born to consanguineous parents who presented with cumulative features of PHID, H syndrome, FHC and Familial RDD in whom a homozygous splice site mutation (c.300 + 1G > C) in the SLC29A3 gene was identified [24]. This evidence concerns the gene SLC29A3 and sinus histiocytosis with massive lymphadenopathy.