Poodineh et al. have been reported that miR-130a-3p could block the expression of Wnt signaling cascade gene (ZEB1, CTNNB1, LRP6, FZD6, Wnt2B) in breast cancer, and highly expressed miR-130a-3p could reduce migration and proliferation in triple-negative breast cancer [32]. This evidence concerns the gene LRP6 and breast carcinoma.