TET1 and squamous cell intraepithelial neoplasia: In 2019, Po-Hsuan Su et al. [65] found increased TET1 and 5hmC correlation from normal to low-grade squamous intraepithelial lesions (LSIL) in the cervix, maximized in high-grade squamous intraepithelial lesions (HSIL), and reduced in invasive carcinoma.