RBPJ and neoplasm: Then, we found that RBP‐Jκ knockdown significantly reduced tumour cell migration (59.67±8.18 cells per microscopic field in RKO‐shR vs. 98.00 ± 6.53 in RKO‐NC, p = 0.007; Figure 2C) and that RBP‐Jκ overexpression markedly induced tumour cell migration in SW480‐R vs. SW480‐NC (98.33 ± 17.56 vs. 56.00 ± 16.82, p = 0.039; Figure 2D).