Furthermore, our Western blot analysis results revealed that downregulation or upregulation of RBP‐Jκ expression in colon cancer cells inhibited or promoted tumour cells to undergo EMT, whereas upregulation or downregulation of TGF‐β1 expression in TAMs reversed the downregulation or upregulation effect of RBP‐Jκ on colon cancer cells (Figure 6D, Figure S4H). Here, RBPJ is linked to colonic neoplasm.