Soluble uric acid exerts an inflammation‐stimulatory effect and induced the production of tumor necrosis factor α (TNFα), interleukin (IL)‐6, and IL‐1β,25 it also involved in the lung injury, COPD (chronic obstructive pulmonary disease), and EP (eosinophilic pneumonia).26, 27, 28. This evidence concerns the gene TNF and chronic obstructive pulmonary disease.