Compared with other SNPs, rs4341787 is in the highest LD (r2 = 0.779) with the AD lead SNP rs7207400 and is an eQTL identified by GTEx for NMT1. Also, in high LD (r2 = 0.775) with rs7207400, rs2049515 could be a risk variant for multiple genes as it is an eQTL for CRHR1, SPPL2C, and NSF (Fig. 5H and Supplementary Table S7). Here, SPPL2C is linked to Alzheimer disease.