DUSP22 (Additional file 1: Fig. 9B) and RPL37 (Additional file 2: Tables 4A, 4B; Additional file 1: Fig. 9C) associated with rate of cognitive decline as measured by the slope of mPACC, and AMPD3 (Additional file 2: Tables 4C, 4E; Additional file 1: Fig. 9D) associated with the slope of CDR-SB and MCI to AD conversion status are also abundantly expressed in microglia. This evidence concerns the gene DUSP22 and Alzheimer disease.