In addition, miR-93-5p (miR-93) mediated Msk2-mediated high glucose-induced chromatin remodelling in the diabetic nephropathy, and overexpression of miR-93-5p constrained TGF-β1-induced EMT and renal fibrogenesis in DN [37, 38]. The gene discussed is RPS6KA4; the disease is liver dysplastic nodule.