Serum levels of bFGF were exclusively higher in RS3PE patients with malignancy [14.21 (7.52, 23.18) ng/mL] than RS3PE patients without malignancy [4.32 (2.88, 7.42) ng/mL], OA [3.23 (1.96, 5.59) ng/mL], and EORA [3.20 (2.20, 5.30) ng/mL]. The gene discussed is FGF2; the disease is cancer.