Among these significant risk factors related to CSF p-Tau/Aβ40, we found HTN was related to aHCV (βstd = −0.52 [95% ci, −0.90, −0.14], p = 0.009) and ΔPACC (βstd = −0.46 [95% ci, −0.88, −0.04], p = 0.037) (Supplemental fig. Here, MAPT is linked to hypertensive disorder.