NR4A1 and breast neoplasm: In addition to these, studies have shown that dairy partial ingredients and their bioactive components can exert inhibitory effects on BC by downregulating ER-αexpression and activity, inhibiting proliferation, metastasis, and angiogenesis of breast tumor cells, inducing apoptosis and cell cycle arrest and sensitizing breast tumor cells to radiotherapy and chemotherapy, which may explain the reason why dairy products have apparent protective effects on hormone receptor-positive BC [33, 103–105].