We also found that KLF5 regulated the expression of multiple genes; for instance, KLF5 overexpression has been reported to promote proliferation and malignant transformation in a mouse pancreatic ductal adenocarcinoma model [44] and promote tumorigenesis and metastatic potential via the NF-κB signal pathway [45]. The gene discussed is NFKB1; the disease is pancreatic ductal adenocarcinoma.