The results of WES led to the identification of 10 new genes that cause an AS-like phenotype (SYNGAP1, VAMP2, TBL1XR1, ASXL3, SATB2, SMARCE1, SPTAN1, KCNQ3, SLC6A1 and LAS1L), all of them previously associated with other neurodevelopmental disorders. This evidence concerns the gene SMARCE1 and neurodevelopmental disorder.