Hence, the systematic comparison of selected omics data was done to identify the important DEGs (stress, endocrine, immune, signalling, and structural) in M. rosenbergii and P. monodon when exposed to WSSV and V. parahaemolyticus/VpAHPND infections focusing on those involved in STAT functioning or potentially associated with JAK-STAT signalling. Here, SOAT1 is linked to infection.