A positive correlation between LDL‐C and PCSK9 levels was observed “without LLT” in not only the general population but also in FH patients,3, 19, 20, 21 whereas this positive correlation disappeared in patients with hypercholesterolemia (in whom some FH patients might be included) “under LLT”.20, 21. Here, PCSK9 is linked to Hypercholesterolemia.