To further investigate the potential mechanism of action of LINC00184 in NSCLC, NCI‐H1359 and A549 cell lines were divided into four groups and transfected with negative control (NC), LINC00184 (LINC00184 overexpressed plasmid), LINC00184 + miR‐524‐5p mimic and LINC00184 + siHMGB2, respectively. The gene discussed is LINC00184; the disease is non-small cell lung carcinoma.