EGFR and neoplasm: In Fig. 3 and Table 1, we demonstrate using AUC of ROC curves and diagnostic tests, that PAI can distinguish tumor from normal tissue with higher accuracy than SAI in cases of low EGFR expression (FaDu, 6.2 % of A431 expression—see Supplemental Material Section S5) and in populations with high individual variance (all cell lines, nearly two-orders of magnitude difference in EGFR expression).