There were no significant differences in age, gender, DBP, WBC, HB, PLT, UA, ALB, T-CHO, TG, LDL, 24 h-TP, urine RBC counts, CRP, complement C3, complement C4, IgA, IgG, IgM, anti-MPO, anti-PR3, BVAS, and the prevalence of DM and cardiovascular diseases among the patients in the four groups (Tables 1, 2). The gene discussed is PRTN3; the disease is diabetes mellitus.