Consistently, p73 isoforms play a key role in the regulation of cancer stemness, epithelial-mesenchymal transition (EMT) and response to therapy across several cancer types (Prabhu et al., 2016; Thakur et al., 2016; Sharif et al., 2019b; Uboveja et al., 2020). This evidence concerns the gene TP73 and cancer.