Serum IGF-1 was significantly lower among female sarcopenic subjects, with a demonstrable trend for a protective effect against sarcopenia in multiple regression models, such that each 1 ng/ml increase in IGF-1 was associated with a 1% decline in the odds of sarcopenia in women (p = 0.095) (Tay et al., 2015). The gene discussed is IGF1; the disease is sarcopenia.