Similarly, several studies have recently reported that PSME3 was overexpressed in breast cancer (BRCA) tissues compared to normal tissues and that BRCA patients with low expression levels of PSME3 had a favorable prognosis compared to patients with higher expression of PSME3 (Chai et al., 2014, 2015; Shi et al., 2015). The gene discussed is PSME3; the disease is breast cancer.