Chi-square test suggested that the expression level of PD-L1 in positive and negative CD86 group was significantly different in HCC specimens (Table 2) (χ2 = 5.182, p = 0.023), and the odds ratio (OR) was 3.200 [95% confidential interval (95% CI), 1.156, 8.854]. The gene discussed is CD274; the disease is hepatocellular carcinoma.