TGFB1 and central nervous system cancer: In addition, Cell Cycle Regulation by BTG Family Proteins (Z-score=-1.633), TGF-β Signaling (Z-score=-1.387), Wnt/β-catenin Signaling (Z-score=-1.342), and Antiproliferative Role of Somatostatin Receptor 2 (Z-score=-1.265), which are important signaling pathways in glioma proliferation and cell cycle regulation, were also inhibited (Figure 4D).