SPPL2C and Anxiety: These overlapping genes include KANSL1-AS1, CRHR1, CRHR1-IT1, SPPL2C, RP11-707O23.5, RP11-259G18.1, MAPT-AS1, LRRC37A4P, PLEKHM1, and DND1P1. These findings identified genes whose genetically regulated expression may confer risk of anxiety, suggesting that genetic variants may confer anxiety risk by regulating the expression of these genes.