It is noteworthy that 10 genes (KANSL1-AS1, CRHR1, CRHR1-IT1, SPPL2C, RP11-707O23.5, RP11-259G18.1, MAPT-AS1, LRRC37A4P, PLEKHM1, and DND1P1) showed TWS in both datasets (i.e., PsychENCODE and GTEx), implying these genes are promising candidate genes for anxiety. The gene discussed is PLEKHM1; the disease is Anxiety.