Considering all samples (Figure 3, upper panel), the allotype MICB*004 and the amino acid residue that defines it, 75-N, both related to the missense mutation rs3131639/A, and the presence of K at residue 101 from HLA-DRB1 (related to rs9296942/T), are overrepresented among COVID-19[+] when compared to COVID-19[-] (p < 0.005) and the general population (p < 0.05). Here, HLA-DRB1 is linked to COVID-19.