Moreover, the combined analysis of CXCR3 and CD161 showed the presence of cells expressing both markers (about 15% of Tconv cells) that are reminiscent of pathogenic Th17.1 cells (36, 37), that produce both IL-17 and IFN-γ, previously described in autoimmunity or autoinflammation (38). The gene discussed is IFNG; the disease is Autoimmunity.