Tahara et al. (2014) also reported that the abundance of Fusobacteria was associated with MSI, CIMP, TP53, CHD7, and CHD8 mutation status but not KRAS and BRAF. However, a Japanese study reported that higher abundance of Fusobacteria in CRC tumor tissues was associated with KRAS mutation (Yamaoka et al., 2018). This evidence concerns the gene TP53 and neoplasm.