However, after adjustment for age, sex, hypertension, diabetes mellitus, eGFR, and NT-proBNP, log TMAO was not found to be an independent predictor of MACEs and death at 30 days (HR: 3.37, 95% CI: 0.89–12.70, p = 0.073; HR: 3.34, 95% CI: 0.62–17.90, p = 0.160, respectively) and 6 months (HR: 2.19, 95% CI: 0.73–6.59, p = 0.161; HR: 1.67, 95% CI: 0.40–7.04, p = 0.486, respectively) (Supplementary Table S2). This evidence concerns the gene NPPB and diabetes mellitus.