FPR2 and meningitis: Another study using a mouse model of Streptococcus suis-induced meningitis, indicated that AnxA1 exerted anti-inflammatory effects via attenuating leukocyte infiltration, inflammatory mediator production, and astrocyte or microglial activation in the brain, along with decreasing neutrophil adherence to the endothelium through FPR2, thus inhibiting meningitis progression.