MRC1 and neoplasm: Furthermore, weaker STC-1 expression was seen in epithelium of EC with a higher grade (p = 0.030), LVSI (p = 0.050), deep myometrial invasion (p = 0.003), large tumour size (p = 0.001), and MMR deficiency (p = 0.048), suggesting a protective role of STC-1 in EC (Table 2).