APOE and Alzheimer disease: On the other hand, late-onset AD is known for being strongly associated with the presence of apolipoprotein E (ApoE) \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\epsilon$$\end{document}ε4 allele2.