In another functional analysis, the role of PSMB8 was recapitulated in mucinous ovarian carcinoma pathogenesis, which identified PSMB8 as a mediator between antigen presentation of exogenous antigen via MHC class I molecules and the noncanonical nuclear factor kappa-light-chain-enhancer of activated B cells (NIK/NF-kB) pathway7. Here, PSMB8 is linked to ovarian mucinous adenocarcinoma.