ADCY1 and pancreatic adenocarcinoma: We downloaded two independent PAAD datasets from the GEO database (GSE84129 and GSE62452 datasets) to analyze the diagnostic and prognostic value of GNG7 and ADCY1. In the GSE84129 dataset, PAAD patients with high survival time (more than 24 months) have significantly higher mRNA expression of GNG7 and ADCY1 than patients with short survival time (no more than 24 months) (Fig. 7A,B).