CXCL8 and neoplasm: A study reported that CXCL8, a pro-inflammatory chemokine, plays an important role in metastasis by associating with tumour-related inflammation [27–30] and inducing the risk of OLK and OSCC, such as in the case of betel quid chewing and smoking [41, 42], but the regulatory pathways are still not reported to date.